Viroids have been discovered in 1971 by the specialist of plant diseases T. O. Diener. These particles, smaller than viruses, are made of a single stranded RNA and do not have protein coat (capsid).
The RNA of viruses do not code for any protein and have a very important secondary structure. As viroids do not contribute to the production of any protein, it is difficult to see how they affect the host cell. The most probable hypothesis is that they disturb the normal expression of the genes at the level of the RNA messenger (mRNA) thus affecting all the cellular metabolism. They only affect crops having complex levels of organisation. If some of them cause few or no apparent damage to the plant, others are responsible for the development of serious diseases. Viroids differ from viruses on six points :
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